SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2647e24dc0fa236376a241d430ae6b8958cbe24b8d4edad71bba054c9aba94ec' 
  AND token = '6x9KG9mwunT9jSxXdSSmMT7ClB9Tf1XjjeqVu2Hko+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}