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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b465fbda666f461c94287227325cd6b227ea657f82f44d395dd1e7f113131ac' 
  AND token = 'JeddGGqmIO51MKkcPqMe3mZ4ed0Mhpq8NHj5+yK55g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}