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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2269d90b58d8868d0cab5b1084622265e1084b5ae72a44b88ed04f41ccba05' 
  AND token = 'vIN6/XViUrYe0ZlETsc0pNbq9XAI+IxXtRqrk2mYEvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}