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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc81779b4482bead6ffc6e3206b71ac4bba1ced0db19a2137c41556698b34248' 
  AND token = 'sjnk8/x1PNnKZ075H3zIEXjku/4gpRNvHmmO8Lp4DE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}