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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '436cd28ced0d2a0f61609bed7f3177cd6f4ab2546355fbee8599dc2e516f5aca' 
  AND token = '+86g5WKzTQFXRQadaZNYnItnSlWjV+jvMMo6rDjyDCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}