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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ced3a8114b21c00015eafbdcde0a070cd5c461b01f2d5e5afbaa260decdd4d' 
  AND token = 'lfcqpKCSG6P1s6lLhLGsu32iNfqe86Z7KNiAP3PTbt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}