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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b61cbba8918e9e2220fc5751cbfa401014c1e8566dd533a85c8bd4d689ac6e41' 
  AND token = 'leR7yhLEQAzpCLWQd+cLV0DQjNGlpPr2Jt1+OcLh9IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}