SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec2ec102575b6cb031e66aa3d0cb5162e2cde0694352b0085e358a7c85bd1f5e' 
  AND token = '+5J3YSOMCRUjIwvAQwH4Ivd5EueNrT8bdeIwYCBgeCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}