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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca1dbe29fc201248a5e963e56705d1a8bf6b63404ab995fafccc276aa1225e6a' 
  AND token = 'p1X5+3kCYprUY7jb0lPXxpjBUI3HsOzzsge+1SVXlMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}