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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8da8c2012e85c60c587313a8596229b7d4c4b520e098bfa4ef1802a157df39' 
  AND token = '82bGWDhDALR7lPa3dPVhUr1zDutG5ifKCKEqyHrr5aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}