SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff47ba41a7f9266a01a91f8e2318012c02d036f32478ee848c5623e4b4e3f3f' 
  AND token = 'Rf5YFJscrVsTOwUqScYxC7eH+n/4DISTRw/m/A3tzZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}