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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654611ccbade9993d410b95709983ef1ce1d4f1c705bf075f4fac5ad3bff7125' 
  AND token = 'SmhyLLRUzGbV0qk0+R535FTpYLVhxhk4rNjf5vK+888=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}