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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad9464a61828ef01c5811b4f82dcf72c334cbf4fb4d9980672304b870eb56961' 
  AND token = 'cdl+wDQDeZ5LCpk7o163t12c/RjvyxYjk8ZagUJ4vuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}