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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a3cb23d2aea2b0e772a4aae2817f730fcafdb4429552b6697eaa4d46e8d6b7a' 
  AND token = 'PVyPe2PdYiGIiUTKAbnCJw5tQbOXGvdrWbRcak6c4/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}