SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e79f0ddf9d5919a9afafc21959de4034aae5d4435b49f436ce3f7d9906f538' 
  AND token = 'uOsFn9ks3DqCd3KNKuGCMXbvl19k9PstmlPDx3gJcrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}