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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '065b933a74d0af38ddd38c0c04f9c694226f3c7f5e58651df19529eab4fc0403' 
  AND token = 'uSJpS33K+lQVkb2iSmmhXM8EoP94BNgJpccjwuWfeY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}