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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29159edb586c91ac3a5d535be6dfe2eb268814824118293fe374f53cbd195605' 
  AND token = 'iJkLQ4LzfRlx9AZtxA431rDo7fUc3DIaGPcmHAqOY+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}