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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba106a7b1262a971f53ea9d390a76ad7377c971d1a93e8815f5f2aefc0191225' 
  AND token = 'zpIl2y9aNV4ga9sJcMPYz0KDv0h+2VNNe6tmoUOoRG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}