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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '759aa0b1808b3345283f8e0f0872825c7bbe83c788e52910ef0aba49a65dec1a' 
  AND token = 'lIoiPqdWF87uF+b1M5OjujbAx3dU3JkIiXDIict4aXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}