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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b6679b9d6dc659ffd6e08551f4ddaa4c17d23e01807b1abd3e5d595ba7139c' 
  AND token = 'G8Os/jOqmkpX/84k9yavjyI9PJKDnRrur5L5H7lTcEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}