SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '329689303986ffdad07b817515b2f17a55e8dfc5ab59d5303d9e3063c531d1b1' 
  AND token = 'Hgzt6+Xfp8z7BTdf7W2DehCzIVyduneZz5B6qEMRiM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}