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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78bfde8972cbd1c03f72d85c4c88490fa8c6121bb6c8eaf2c1f838baac323db6' 
  AND token = 'pl4v8LgKvh7i411jPBdKXy7b6f4C5LHYludcdnMEQ0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}