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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0c504f3d76dd946600d6875221b2bcee7f803221fc572e9dbbebda8a2bade2' 
  AND token = 'Tdyf7QS7OI+1m3Fp2TUai2oy/3ET5AbP7VtorUt78tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}