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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '421327a1db9e2d3efbdc501e4750c00785897c9a3352732146a8f35aff419720' 
  AND token = 'FX1zrIEU7v6r+QjFX1pqQrok+fCu7HOzC9KUk6Rdq1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}