SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46acc1cfa2057ce919bc4dced90875be9f5c73a4b84a0d6f819f25b413fb5852' 
  AND token = 'PwKxYEaQC8VO6BNM5buYLJD2d7jqDjhdn30dvIcY47A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}