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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff9729d8c0c2f082489e56534bd8846e59e7a443d9ad5a7246a5fc236adf7437' 
  AND token = 'SMymK6AkstsGan42dfNhHqLgIGT08LBTGMagyAv9Gxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}