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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec52800c5aaadf92f8c2ac573c4b5c2eb9b9d49b22e3d47e458e1b16e943f4b1' 
  AND token = 'qx0NlhtLT1sRx6gdHdDXSRDuPnHBdyFRbsk3ToEIdBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}