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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e737c8b89e0f4eb024c3df2e409b9cb036f34befd5029da095a2a38121a66f' 
  AND token = 'PBsGVAMZEO5z2oUyxs7csUs+fIcyTq8akbxSJzL+1do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}