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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95729d7712798b3ee8c65ea0dd555e02da24a02e8c4a12d9755a9a07a4740775' 
  AND token = 'Y94XdD8fjtUkuaF5ZDj38ovFmbuP/W7dkTgNpeBEOhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}