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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c1b1dd483d788264d62d9dc53421047b27b4b26154b07bde467f1abc513622' 
  AND token = 'U0uuKMZQ4d+bMj6iqaniKd3csL21WMdg5VUQ5iByJ08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}