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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e07c3d5dcdcd298ef8c31e84400151ed502649b04e80925d7b5bf43d7f039d2d' 
  AND token = 'uJUTNTlIM5zkwRmAjb6owSd7Bh+V0x5t7BqXbj0O7SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}