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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a369ec60aa3f485549b68d51bd04277fadd6afa2209294eeba4b8ad3c31bafc' 
  AND token = 'gp0KpMU2Y2g6x2n0gsdgpT9rUUmGsMwCrH0xPNWjKl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}