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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aa05be5a889736b1ba613eb5686b14a1e512e41afb2e4eae21332996e9bc1a4' 
  AND token = 'kYbOtOcNCfOLnVbMIRQsXFv5+tAEEBsZmZ2CaZi+44M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}