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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aef250b3f9ad993ff6b999a15cef1bac65001ed6b8c9461bc1994888c9d2637' 
  AND token = 'IwWM8O5A98+/SUDDD3UDPLglHAizApBWJs8NdB8Iz+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}