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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e432ef338f5420fcf872fb5a2414b5bc95e1a79d2d3030fd3417142bf4f2f21f' 
  AND token = 'iSZ/VWhQYDlyywRA65CVx2e3gRDpnCnZicr8fCDzBnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}