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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04350f114be4fd01dc665b6cee53fba1ff89c15d1302f8dea63abf57ee6745c3' 
  AND token = '59HCW6q9G2r0BFWa/C92noQioAxDpcPU3FuZ1t2MVpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}