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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a51371e4917670ad37fc26f206b8a004d12ce84a166e6b7513892e3f2835e9' 
  AND token = 'OPcf88Okmzb4dejgtYIOhv1BZppLS6k7Dwha2a7rQq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}