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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42e4ac6c63b817a5f347d4502dbbc3e020fb67ced2f985baefea730ab3ac3a99' 
  AND token = 'JKUXBxSBcc+OI15PLU4kluxKyy8EWubgHrZEbKjikjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}