SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a994e6a7c315ab999cf30ac01ab9d649c66b753f7cbac3a30fae2bcf5d08f05f' 
  AND token = 'j+FP5ZB66dSi0LwEfLx1yxfQOVOh2WF8HucSyjuAeB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}