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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a8e51b26343660b55cf2846e43a560cceb344be2184fd5b5411b98054c52441' 
  AND token = 'BbH9Ev3qEKpTbFqr2ndx7U7kE4K0k7lCv2sRpGkDBQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}