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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6e0f7686de4f34cf197d240cac4abc83ca6b59f1d970e2914d3f6802dcfe124' 
  AND token = 'MGUJwuoCsfBHDa5cYliUOsWZLQaVaMn4ovbNyLEXd7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}