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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '041845e5d5a709ba48ba5d6d85ebc258b306d41835f5cefff50f0b13c188a6af' 
  AND token = 'fEcrMR1q12dVUtRjiBxQXyt2LYc5GdSTeYhRxe9cGNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}