SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c299ce8b19d10414fd2452428d37ee4e953a9e239d64c1a0784af7c32b79be' 
  AND token = 'TGdsrqM+oaYh7F8vL2NulUVZkUCVREY+K6ac9XAiLLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}