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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5548506a6382a118311b0bb1f96b1e00b69e6f865457aa2906d46b99d98bacc0' 
  AND token = 'tlxUWoG6wQKFdCptmTK5XfOSoeD4wbJx+FUIp99QD54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}