SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c8764dbaf83a5766b67be3888b73741f0dfa1ae6cca9b273b702f71b06a2f3' 
  AND token = 'u6wa6xqVkB1I2kpkj/swoMFt9MDs3S/0OEoWSUgnsKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}