SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57bb7ed592bd0396122c1f454f7c3ad9c6ca161b3b7e0f79c06c039ad223708f' 
  AND token = 't1ofA6S/W0sWuJXFkJrDZQfzxZ38cHOhiAGx6QCpQB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}