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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3144ad2b708e0b0b5c1c7c0363e5eb02bc62c7115b3852ae7904ec4fa1501252' 
  AND token = 'XqLWE1aHPHajEG6PScrveFzZMwLu0NlmnRNpWuCdJ/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}