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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4136a2324b480a73dc989fd6e505ac9b7e9ce43cba15315826ec1c75330dce27' 
  AND token = 'XatEnVEQZE0HLh+hOdQFJu6a23xiodFoSQufXbGbUzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}