SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8106430ce0240c2d131d4b582b87c7c75d7f640b68532405849538593a8de0' 
  AND token = 'xGsTMLAYkRx8ovwce2ZpqHOh9JxYJ1rGY4kmO3CqTiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}