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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '918c19c2e8d8e49cd55cebc33c9a3db11e6c4f9f031ee4bfa351a9474964396f' 
  AND token = 'eMyJx/f+vPbABJGw6gZS5ihfJgsjMhUxmHwcw6NnvbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}